GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs9369898 | 1 | rs9473550 | chr6:49385182 | CENPQ | chr6:49431096-49460820:+ | -0.39 | -8.5 | 4.43E-16 | Homocysteine levels |
| BLCA | cis | rs9473555 | 1 | rs9473552 | chr6:49387154 | CENPQ | chr6:49431096-49460820:+ | -0.28 | -5.66 | 2.91E-8 | Folate pathway vitamin levels |
| BLCA | cis | rs9473555 | 1 | rs9473552 | chr6:49387154 | MUT | chr6:49398994-49431031:- | 0.28 | 5.53 | 5.94E-8 | Folate pathway vitamin levels |
| BLCA | cis | rs9473555 | 1 | rs9473553 | chr6:49395977 | CENPQ | chr6:49431096-49460820:+ | -0.28 | -5.69 | 2.46E-8 | Folate pathway vitamin levels |
| BLCA | cis | rs9473555 | 1 | rs9473553 | chr6:49395977 | MUT | chr6:49398994-49431031:- | 0.28 | 5.5 | 6.86E-8 | Folate pathway vitamin levels |
| BLCA | cis | rs9473555 | 1 | rs9473555 | chr6:49409487 | CENPQ | chr6:49431096-49460820:+ | -0.28 | -5.82 | 1.22E-8 | Folate pathway vitamin levels |
| BLCA | cis | rs9473555 | 1 | rs9473555 | chr6:49409487 | MUT | chr6:49398994-49431031:- | 0.27 | 5.46 | 8.78E-8 | Folate pathway vitamin levels |
| BLCA | cis | rs9473555 | 1 | rs9473560 | chr6:49427918 | CENPQ | chr6:49431096-49460820:+ | -0.28 | -5.65 | 3.17E-8 | Folate pathway vitamin levels |
| BLCA | cis | rs9473555 | 1 | rs9473560 | chr6:49427918 | MUT | chr6:49398994-49431031:- | 0.28 | 5.51 | 6.48E-8 | Folate pathway vitamin levels |
| BLCA | cis | rs9473555 | 1 | rs9473561 | chr6:49428755 | CENPQ | chr6:49431096-49460820:+ | -0.28 | -5.65 | 3.17E-8 | Folate pathway vitamin levels |
| BLCA | cis | rs9473555 | 1 | rs9473561 | chr6:49428755 | MUT | chr6:49398994-49431031:- | 0.28 | 5.51 | 6.48E-8 | Folate pathway vitamin levels |
| BLCA | cis | rs9473555 | 1 | rs9473563 | chr6:49453651 | CENPQ | chr6:49431096-49460820:+ | -0.29 | -5.82 | 1.25E-8 | Folate pathway vitamin levels |
| BLCA | cis | rs9473555 | 1 | rs9473563 | chr6:49453651 | MUT | chr6:49398994-49431031:- | 0.26 | 4.96 | 1.07E-6 | Folate pathway vitamin levels |
| BLCA | cis | rs947583 | 1 | rs947583 | chr6:136133659 | PDE7B | chr6:136172834-136516708:+ | 0.23 | 4.1 | 5.08E-5 | Phosphorus levels |
| BLCA | cis | rs948562 | 1 | rs948562 | chr11:58347765 | CNTF | chr11:58390146-58393203:+ | 0.3 | 3.91 | 0.00011 | Lymphoma |